AutoNA / Version Releases

AutoNA — Version Release History

Reverse-chronological release history across AutoNA mRNA and aptamer products.

1.0.02026-05-12Cross-cutting

Production release of AutoNA with authenticated job creation, mRNA optimization, mRNA scoring, protein-DNA aptamer screening, collaboration, exports, and operational monitoring.

  • Launched the authenticated AutoNA workspace with registration, email verification, login, password reset, user profiles, and credit-aware access controls
  • Added a unified job dashboard for owned and shared jobs, including status tracking for queued, running, completed, failed, and cancelled work
  • Released mRNA optimization workflows for CDS or protein inputs, configurable UTR lengths and benchmark UTRs, and selectable optimization targets for translation efficiency, half-life, and protein abundance
  • Released mRNA scoring workflows for uploaded sequence sets, including predicted half-life, translation efficiency, protein abundance, benchmark deltas, UTR secondary-structure metrics, sorting, and CSV/Excel export
  • Released protein-DNA top-binder selection with manual or CSV input for protein and aptamer pairs, top-percent selection, optional MSA-enabled folding, ranked sequence tables, and result downloads
  • Added mRNA result visualization with chart payload storage, generated and benchmark sequence tables, model and cell-type prediction provenance, and downloadable result files or ZIP packages
  • Added job sharing so users can grant and remove collaborator access, view shared jobs, and invite new collaborators by email
  • Added admin tools for user management, credit allocation, user types, test job submission, model registry, species, 5' UTR and 3' UTR libraries, plus platform usage statistics
  • Added production operations support with workhorse webhooks, Celery queue checks, public status reporting, incident reports, health dashboards, and alert notifications
0.3.02026-04-15Cross-cutting

Unified job dashboard across mRNA and aptamer pipelines, plus visualization upgrades.

  • Single dashboard view for mRNA and aptamer jobs
  • Custom data-visualization plugins for proprietary metrics
  • Reduced average job latency by ~30%
  • Improved error messaging on invalid input sequences
0.2.02026-01-20Aptamer

Structure prediction, molecular docking, and structural bioinformatics module added to the aptamer pipeline.

  • Structure prediction integrated into AptaBLE workflow
  • Molecular docking against user-supplied protein targets
  • Structural bioinformatics summary report
  • Counter-selection against the human proteome enabled by default
0.1.02025-10-08mRNA

Initial AutoNA beta — co-optimal mRNA design across half-life, translation efficiency, and protein abundance.

  • Beta release of co-optimal mRNA design
  • Three-property optimization in human cells
  • Browser-based no-code interface
  • Mailto-based access provisioning